1.5M ratings
277k ratings

See, that’s what the app is perfect for.

Sounds perfect Wahhhh, I don’t wanna
dduane doodleholic
currentsinbiology:
“ Take note all athletic scientists!
Cartilage damage could be repaired
Unlike our bones, the cartilage inside our joints is not vascularized (i.e., it has no blood vessels). This is one reason why cartilage does not heal well...
currentsinbiology

Take note all athletic scientists!

Cartilage damage could be repaired

Unlike our bones, the cartilage inside our joints is not vascularized (i.e., it has no blood vessels). This is one reason why cartilage does not heal well after an injury. In athletes in particular, joint injuries often result in cartilage degeneration and arthritis. The process is chronic and irreversible, and to this day, no effective treatment exists.

EPFL scientists Dominique Pioletti and Harm-Anton Klok have developed a hydrogel that promotes cartilage regeneration. In a joint, cartilage-producing cells only respond to treatment if they are mechanically stimulated at the same time, for example in the knee joint when a person is walking. To exploit this fact, the scientists created a hydrogel that delivers a therapeutic drug to the cells only when they are undergoing repetitive movement. The results of their work, which is part of the “Smart Materials” Swiss National Research Project (PNR 62), have been published in the journal Biomaterials.

Caption: Heated by movement, nanostructures in the hydrogel matrix let go of the drugs it contains.

Credit: EPFL

medicine