Pork Chop is fattening up for the winter and still being the Grade-A Dork™ I remembered him as before heading off to college in the summer.
Scientists show how drug binds with ‘hidden pocket’ on flu virus
A new study led by scientists at The Scripps Research Institute (TSRI) is the first to show exactly how the drug Arbidol stops influenza infections. The research reveals that Arbidol stops the virus from entering host cells by binding within a recessed pocket on the virus.
The researchers believe this new structural insight could guide the development of future broad-spectrum therapeutics that would be even more potent against influenza virus.
“This is a very interesting molecule, and now we know where it binds and precisely how it works,” said study senior author Ian Wilson, Hanson Professor of Structural Biology, chair of the Department of Integrative Structural and Computational Biology and member of the Skaggs Institute for Chemical Biology at TSRI.
The study was published in the journal Proceedings of the National Academy of Sciences.
Rameshwar U. Kadam, Ian A. Wilson. Structural basis of influenza virus fusion inhibition by the antiviral drug Arbidol. Proceedings of the National Academy of Sciences, 2016; 201617020 DOI: 10.1073/pnas.1617020114
I get jealous really easily but not like an angry vengeful jealous more like a really sad lonely jealous because everybody likes everybody more than they like me and I really really don’t blame them.
“Ever see a Fruit Cocktail Tree?”
– Del Monte Fruit Cocktail, Woman’s Home Companion, February 1941
Roger Wilco - Space Quest series (1986 - 1995)
I realized that I hadn’t done any of the Quest series. So here’s Mark Crowe and Scott Murphy’s Roger Wilco. This space janitor will always have a place in my heart, if only for the fact that he at one point travels to his own sequel.
Also, hello to all the new followers. Thanks for stopping by.
This is available on print here.
I highly recommend the movie “Arthur Christmas” to those whose sense of humour tends towards the Practchett-like.
Tumblr blew up I guess??? Pixel Lady!
The thing about Yuri on Ice
Or rather the audience response to it, which is of people starved for sustenance shocked and tearful at being fed a decent meal: it’s not just that it’s a heartwarming queer love story, it’s a heartwarming queer love story set in a more humane (but not unbelievable) world, one populated by characters who are both colorfully drawn and basically good-hearted. There are no antagonists; no one is really malicious or cruel. This is not to say none of the characters ever screw up, because of course they do, but no one in the world of this story is trying to harm anyone else.
Maybe this is in part what @coloredink means by calling it a gift from the brightest timeline. What I’m seeing in the often semi-hysterical audience response–my own included–is that there’s a massive unmet need for this sort of gift. I don’t like to use the word “fluff” because I have a complex about it, which boils down to resentment toward its connotations of insubstantiality, and what Le Guin once said about the bad habit, encouraged by pedants and sophisticates, of considering happiness as something rather stupid. Happiness is not stupid, and stories devoted to furnishing comfort and joy, and hope of love and a more humane world, need not be stupid or insubstantial. Comfort and joy are essential to life. Not just in the hellhole of a year that is 2016, but always.
There’s no reason we should be starved for stories like this.
deepintheshadyglen