Hit the bullseye! : DS9 “Visionary”
- Now what if one of those darts had gotten into his eye? Do you realise I’d be liable for that? Do you know how much money an eye costs? -
Void Pyramid (Willy Elektrix)
“Void Pyramid is a post-apocalyptic RPG set in the spacefaring Egyptian empire.” - Author’s description
Female Endocrinology - overview
General endocrinology info:
- Autocrine - affects same cell
- Paracrine - affects a nearby cell
- Endocrine - affects elsewhere in the body (secreted by glands into the bloodstream)
- Exocrine - secreted by glands into the external environment (eg sweat, saliva)
Steroid hormones
- Oestrogen
- Progesterone
- Testosterone
- Cortisol
Non-steroid hormones
- Glycoproteins (LH, FSH, TSH, hCG)
- Proteins (GH, prolactin, others include insulin, PTH)
- Peptides (oxytocin, gonadotropin releasing hormone)
- Amino acid derivatives (triiodothyronine, thyroxine (T4), adrenalin)
Anterior pituitary secretes LH and FSH (gonadotropins)
Menstrual Cycle
Follicular phase
- prepares follicles for ovulation
- uses LH, FSH, oestrogen
- FSH (from ant. pituitary) stimulates growth and maturation of several primary follicles
- each produce oestrogen which helps regenerate/prepare endometrium
- one follicle eventually becomes dominant and the others degenerate (~day 7)
Preovulation
- Graafian follicle sends a surge of OES through bloodstream
- resulting LH surge prompts next stage - ovulation (~day 14)
Ovulation
- follicle does not enter fallopian tubes
- ovum erupts from follicle
- fimbrae sweep up ovum, muscular contractions help guide it down the tube
Luteal phase
- following ovulation cells of the ruptured follicle enlarge and form the corpus luteum
- corpus luteum produces progesterone, growing for 7-8 days. if no fertilization, growth stops and progesterone slows
Outcome 1: Fertilization
- Egg lives for 12-24 hours
- takes 5 days to reach uterus (fertilization must occur in uterine tube)
- endometrial development continues with progesterone production
- formation of placenta after implantation from trophoblast - it will take over progesterone production and signal corpus luteum to degenerate into corpus albicans
Outcome 2: No fertilization
- no blastocyst means no hCG to ovary
- corpus luteum stops action, degenerates
- drop in progesterone causes constriction of endometrial arterioles - leads to endometrial ischemia
- causes spongy endrometrial tissue to slough off - menstrual bleed
summary:
Niche is a stylish, sim-esque top down strategy title in which you must use selective breeding to ensure the success of an almost extinct race of creatures.
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