McCoy to Kirk Are you out of your corn-fed mind?

McCoy to Spock Are you out of your Vulcan mind?

McCoy to Chekov Are you out of your vodka-soaked mind?

McCoy to Sulu Are you out of your sword-wielding mind?

McCoy to Scotty Are you out of your tartan-wearing mind?

McCoy to Uhura Have you considered an alternative option?