“My dearest beloved fuckos” is a fun, gender-neutral way to begin a speech.
See also: “Esteemed bastards”
“Gentlefolk, Ferals, and Domesticated Cryptids”
“My fellow yees and haws…”
This is some Screwtape-sounding business.
“Your Imminence, your Disgraces, my
Thorns, Shadies, and Gentledevils…”