Similarly, Ronald D. Moore says “it’s a show we all wish we had a second crack at.” Director Rene Auberjonois comments “it was not my happiest time as a director.” Even Alexander Siddig disliked the episode, particularly his own performance. Nana Visitor had given birth to their son the night before he shot the scene where he and Leeta break up, and according to Siddig, he had never been so unfocused on-set as he was when shooting that scene.

Let He Who Is Without Sin… (episode) - Memory Alpha, the Star Trek Wiki

Another website said that their son was born at about 11 PM, and then Sid went to the set for 5:30 AM to start filming the episode.

Dude. Both my husband and I were totally unable to Human for about twenty-four hours after the birth of our daughter. I cannot imagine going to work!